A newly identified bat coronavirus, HKU5-CoV-2, discovered in China, is drawing global attention due to its potential to infect humans. Researchers warn that this virus is just a small mutation away from becoming highly infectious, similar to previous pandemic-causing viruses, Daily Mail reported.
What is HKU5-CoV-2 virus in China?
HKU5-CoV-2 is a novel coronavirus found in bats, closely related to the Middle East Respiratory Syndrome (MERS) virus, which has a high fatality rate. This virus utilizes the ACE2 receptor to enter human cells—the same pathway used by SARS-CoV-2, the virus responsible for COVID-19. While HKU5-CoV-2 currently infects only bat cells, laboratory studies indicate that a minor mutation in its spike protein could enable it to bind effectively to human cells
Potential for Human Transmission
Scientists have expressed concern that HKU5-CoV-2 could spill over to humans, especially if it passes through an intermediate host like minks or civets, animals known to facilitate cross-species virus transmission. The virus’s ability to thrive in humid conditions further increases the risk of mutation and interspecies transmission
Current Status and Precautions
As of now, there are no confirmed human infections of HKU5-CoV-2, and its symptoms remain unknown. However, the scientific community emphasizes the importance of close monitoring due to the virus’s resemblance to previous pandemics and its potential for human adaptation
Importance of Vigilant Surveillance
The discovery of HKU5-CoV-2 underscores the necessity for robust surveillance systems to detect and respond to emerging viral threats promptly. Experts advocate for enhanced monitoring of wildlife and strict regulation of wildlife trade to prevent potential zoonotic spillovers
In conclusion, while HKU5-CoV-2 has not yet infected humans, its similarities to deadly coronaviruses like MERS and SARS-CoV-2 make it a virus of significant concern. Continued research and global vigilance are crucial to mitigate the risk of another pandemic.
